What is Peptide Mass Calculator?
A peptide mass calculator is an essential tool for biochemistry researchers and pharmaceutical developers to determine the molecular weight of amino acid sequences. This crucial calculation helps in mass spectrometry analysis, drug development, and protein characterization. Our advanced calculator supports both single-letter and three-letter amino acid codes, providing accurate results for academic research and biotechnological applications.
Peptide Mass Calculator
Peptide Mass Formula
The molecular weight calculation follows: MW = Σ(amino acid masses) + 18.0153 (H₂O). Each amino acid's atomic composition is calculated using latest IUPAC atomic weights. Our algorithm accounts for post-translational modifications and disulfide bonds when specified.
How to Use
Simply enter your peptide sequence using either 3-letter codes (separated by hyphens) or single-letter codes. Our intelligent parser automatically detects the format. Click calculate to get instant molecular weight results in Daltons. Use the clear button to reset inputs. Bookmark the page for quick access during lab work.
Amino Acid Mass Table
| Amino Acid | 3-letter | 1-letter | Mass (Da) |
|---|
Advantages & Disadvantages
Advantages:
- Instant calculation saves laboratory time
- Eliminates manual computation errors
- Supports multiple input formats
- Free access for academic research
- Mobile-friendly interface
Disadvantages:
- Doesn't account for rare modifications
- Limited to linear peptides
- Requires internet connection
- No isotopic distribution shown
- Cannot handle branched peptides
FAQs
What input formats are supported?
Our calculator accepts both 3-letter codes (e.g., GLY-SER-ALA) and single-letter codes (e.g., GSA). Mixed case inputs are automatically converted.