What is a Peptide Calculator?
A peptide calculator is an essential biochemical tool that calculates molecular weight of amino acid sequences. Researchers use it for peptide synthesis, drug development, and protein studies. This scientific calculator helps determine exact molecular mass, crucial for experimental preparation, dosage calculations, and quality control in pharmaceutical manufacturing. Accurate peptide calculations are vital for mass spectrometry analysis, HPLC purification, and ensuring proper molar ratios in chemical reactions.
Peptide Calculator
Formula Used
Molecular Weight = Σ(Residue Weights) + Molecular Weight of Water (18.015 g/mol)
Each amino acid has specific molecular weight. Example: Alanine (A) = 89.09 g/mol
How to Use
1. Enter single-letter amino acid sequence (e.g., "AGHIL")
2. Add optional additional molecular weight
3. Click Calculate
4. Results show total molecular weight including water
5. Use Clear button to reset inputs
Amino Acid Molecular Weight Table
| Amino Acid | 1-Letter Code | Molecular Weight (g/mol) |
|---|---|---|
| Alanine | A | 89.09 |
| Glycine | G | 75.07 |
| Histidine | H | 155.16 |
Advantages & Disadvantages
Advantages:
- Quick calculations for complex sequences
- Eliminates manual calculation errors
- Saves research time
- Free accessibility
- Supports various research applications
Disadvantages:
- Requires basic biochemistry knowledge
- Limited to natural amino acids
- Doesn't account for post-translational modifications
- Depends on input accuracy
- No isotope calculations
FAQs
1. How accurate is the peptide calculator?
The calculator uses standard amino acid molecular weights with accuracy up to two decimal places. Results are theoretical and based on unmodified sequences.